Focus
Huperzine A
Huperzine A is an acetylcholinesterase inhibitor with safety data but weak pre-workout efficacy evidence.
How it counts: Counts toward Focus, not the grade
Scored against its clinical dose in the Focus sub-score (and any award that uses it), but it doesn’t move the overall grade.
- Clinical dose
- 50–200 mcg
- Safety ceiling
- 400 mcg
- Evidence
- weak
- Category
- Focus
Evidence summary
Research confidence: low
Phase Ib trial in healthy elderly adults dosed 100/200/300/400 mcg twice daily per week-long step, producing 30-40% RBC-AChE inhibition at 100 mcg rising to >50% at 400 mcg; well tolerated through 400 mcg BID.
Research sources
Dosed at or above clinical in
- Bucked Up Mother Bucker200 mcg
- Alpha Lion SUPERHUMAN Extreme200 mcg
- Gorilla Mind Gorilla Mode200 mcg
- Transparent Labs STIM-FREE Pre-Workout100 mcg
- KAGED Pre-Workout Elite100 mcg
- Gorilla Mind Gorilla Mode Base Pre-Workout100 mcg
- Raw Nutrition Thavage Pre-Workout100 mcg
- Cellucor C4 Ultimate Pre-Workout50 mcg
- BodyTech Elite Altered Strength Pre-Workout50 mcg
- BodyTech Elite Altered Strength Stim-Free Preworkout50 mcg
- JYM Supplement Science Pre JYM High-Performance Pre-Workout50 mcg
- Cellucor C4 Original Pre-Workout50 mcg